Horizon Europe UNIFIED project launched to put patient voices at the heart of healthcare decisions
4 November 2025
Clinical outcomes that are measured in clinical trials and used to guide regulatory and health technology assessments often fail to reflect what truly matters to patients. The newly launched UNIFIED (Unifying Framework for Patient-Centred Clinical-study Endpoints Derived from Digital Health Technologies) project resolves to find solutions, with contributions of Paul Groth and the Intelligent Data Engineering Lab (INDElab). This five-year, €27 million global public-private partnership is funded by the Horizon Europe Innovative Health Initiative Joint Undertaking,
Copyright: UvA
We are excited to participate in this breakthrough project where we are bringing our expertise in AI and data integration to help bring patient’s voice into health treatments.Prof. Paul Groth
Novel methods and benchmarks
INDElab will be developing novel methods and benchmarks that make use of AI foundation models for data integration in a robust and explainable way. This builds on INDElab’s existing expertise in data integration using foundation models.
The impact five years from now
In the next five years, UNIFIED will build a harmonised, evidence-based framework and consensus-based recommendations to integrate the following into healthcare decision-making:
- Patient preference information (PPI)
- Clinical outcome assessments (COAs)
- Digital health technology (DHT)-derived measures
This will be tested in five medical domains: paediatric radiation oncology, lung cancer, Parkinson’s disease, obesity, and juvenile idiopathic arthritis.